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Index > Protein center > Sipa1l1(Gene name) > Mouse
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  • Sipa1l1 (Gene name),
  • Signal-induced proliferation-associated 1-like protein 1 (Protein name ),  SI1L1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Sipa1l1(Kiaa0440);
    Protein name:
    Signal-induced proliferation-associated 1-like protein 1(SIPA1-like protein 1);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with DLG4, PDLIM5, PDLIM7 and PROSAPIP1. Interacts with the actin cytoskeleton (By similarity). Interacts (via PDZ domain) with EPHA4 (via PDZ motif); controls neuronal morphology through regulation of the RAP1 (RAP1A or RAP1B) and RAP2 (RAP2A, RAP2B or RAP2C) GTPases.
    Function:
    Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F-actin. Contributes to the regulation of dendritic spine morphogenesis.
    Subcellular Location:
    Cytoplasm cytoskeleton Cell junction synapse postsynaptic cell membrane postsynaptic density Cell junction synapse synaptosome Associated with the actin cytoskeleton. Detected at synapses and dendritic spines of cultured hippocampal neurons.
    Protein Attributes:
    Sequence length:
    1782
    Sequence:
    50:
    MTSLKRSQTE | RPVTADRASV | VSTDGAPKVH | TDDFYMRRFR | SQNGSLGSSV | 
    100:
    MAAVGPPRSE | GPHHITSTPG | VPKMGVRARI | ADWPPRKENV | KESSRSSQEI | 
    150:
    ETSSCLESLS | SKGSPVSQGS | SVSLNSNDSA | MLKSIQNTLK | NKTGPAESMD | 
    200:
    SRFLMPEAYP | SSPRKALRRI | RQRSNSDITI | SELDVDSFDE | CISPTYKSGP | 
    250:
    SLHREYGSTS | SIDKQGTSGD | SFFDLLKGYK | DDRSDRGPTP | TKLSDFLITG | 
    300:
    GGKGSGFSLD | VIDGPISQRE | NLRLFKEREK | PLKRRSKSET | GDSSIFRKLR | 
    350:
    NAKGEELGKS | SDLEDNRSED | SVRPWTCPKC | FAHYDVQSIL | FDLNEAIMNR | 
    400:
    HNVIKRRNTT | TGASAAAVAS | LVSGPLSHSA | SFSSPMGSTE | DLNSKGSLGM | 
    450:
    DQGDDKSNEL | VMSCPYFRNE | IGGEGERKIS | LSKSNSGSFS | GCESTSFESA | 
    500:
    LSSHCTNAGV | AVLEVPKESL | MLHLDRVKRY | TVEHVDLGAY | YYRKFFYQKE | 
    550:
    HWNYFGADEN | LGPVAVSIRR | EKPEDMKENG | SPYNYRIIFR | TSELMTLRGS | 
    600:
    VLEDAIPSTA | KHSTARGLPL | KEVLEHVIPE | LNVQCLRLAF | NTPKVTEQLM | 
    650:
    KLDEQGLNYQ | QKVGIMYCKA | GQSTEEEMYN | NESAGPAFEE | FLQLLGERVR | 
    700:
    LKGFEKYRAQ | LDTKTDSTGT | HSLYTTYKDY | EIMFHVSTML | PYTPNNKQQL | 
    750:
    LRKRHIGNDI | VTIVFQEPGA | QPFSPKNIRS | HFQHVFVIVR | AHNPCTESVC | 
    800:
    YSVAVTRSRD | VPSFGPPIPK | GVTFPKSNVF | RDFLLAKVIN | AENAAHKSEK | 
    850:
    FRAMATRTRQ | EYLKDLAEKN | VTNTPIDPSG | KFPFISLASK | KKEKSKPYPG | 
    900:
    AELSSMGAIV | WAVRAKDYNK | AMEFDCLLGI | SSEFIVLIEQ | ETKSVAFNCS | 
    950:
    CRDVIGWTSS | DTSLKIFYER | GECVSVESFI | SGEDIKEIVR | RLQFVSKGCE | 
    1000:
    SVEMTLRRNG | LGQLGFHVNY | EGIVADVEPY | GYAWQAGLRQ | GSRLVEICKV | 
    1050:
    AVATLSHEQM | IDLLRTSVTV | KVVIIPPHDD | CTPRRSCSET | YRMPVMEYQM | 
    1100:
    NEGISYEFKF | PFRNNNKWQR | NASKGAHSPQ | VPSQLQSPMT | SRLNAGKGDG | 
    1150:
    KMPPPERAAN | IPRSISSDGR | PLERRLSPGS | DIYVTVSSMA | LARSQCRNSP | 
    1200:
    SNLSSSSETG | SGGGTYRQKS | MPEGFGVSRR | SPASIDRQNT | QSDISGSGKS | 
    1250:
    TPSWQRSEDS | LADQMEPTCH | LPAVSKVLPA | FRESPSGRLM | RQDPVVHLSP | 
    1300:
    NKQGHSDSHY | SSHSSSNTLS | SNASSAHSDE | KWYDGDRTES | DLNSYNYLQG | 
    1350:
    TSADSGIDTA | SYGPSHGSTA | SLGASTSSPR | SGPGKEKVAP | LWHSSSEVLS | 
    1400:
    LADRTLETEG | HGMDRKAESS | LSLDIHSKSQ | GGSSPLSREN | STFSINDAAS | 
    1450:
    HTSTMSSRHS | ASPVVFSSAR | SSPKEELHPT | ASSQLAPSFS | SSSSSSSGPR | 
    1500:
    TFYPRQGATS | KYLIGWKKPE | GTINSVGFMD | TRKRHQSDGN | EIAHTRLRAS | 
    1550:
    TRDLQASPKP | TSKSTIEEDL | KKLIDLESPT | PESQKNFKFH | ALSSPQSPFP | 
    1600:
    TTPTSRRALH | RTLSDESIYS | SQREHFFTSR | ASLLDQALPN | DVLFSSTYPS | 
    1650:
    LPKSLPLRRP | SYTLGMKSLH | GEFSASDSSL | TDIQETRRQP | IPDPGLMPLP | 
    1700:
    DAASDLDWSN | LVDAAKAYEV | QRASFFAASD | ENHRPLSAAS | NSDQLEEQAL | 
    1750:
    VQMKSYSSKD | PSPTLASKVD | QLEGMLKMLR | EDLKKEKEDK | AQLQAEVEHL | 
    1782:
    REDNLRLQEE | SQNASDKLKK | FTEWVFNTID | MS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse SIPA1-like protein 1
    Cat.:
    E6550m
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse SIPA1-like protein 1
    Cat.:
    E6550r
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse SIPA1-like protein 1
    Cat.:
    E6550h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse SIPA1-like protein 1
    Cat.:
    U6550m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse SIPA1-like protein 1
    Cat.:
    U6550h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse SIPA1-like protein 1
    Cat.:
    U6550r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse SIPA1-like protein 1
    Cat.:
    P6550Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse SIPA1-like protein 1
    Cat.:
    P6550Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse SIPA1-like protein 1
    Monoclonal Antibody for Mouse SIPA1-like protein 1
    Monoclonal Antibody for Mouse SIPA1-like protein 1
    Monoclonal Antibody for Mouse SIPA1-like protein 1
    Protein for Mouse SIPA1-like protein 1
    Protein for Mouse SIPA1-like protein 1
    Protein for Mouse SIPA1-like protein 1

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    Recovery
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Olfactory bulb.
      tissue: Testis.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6.
      tissue: Brain.
    3. 3.
      Lubec G. , Kang S.U.
      Submitted (2007-04) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 18-28; 1379-1408 AND 1468-1482;IDENTIFICATION BY MASS SPECTROMETRY
      strain: C57BL/6.
      tissue: Brain.
    4. 4.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Aizawa H. , Yuasa S. , Nakajima D. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:35-48(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 273-1782 (ISOFORM 1)
      tissue: Brain.
    5. 5.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    6. 6.
      "The EphA4 receptor regulates neuronal morphology through SPAR-mediated inactivation of Rap GTPases."
      Richter M. , Murai K.K. , Bourgin C. , Pak D.T. , Pasquale E.B.
      J. Neurosci.27:14205-14215(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EPHA4
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1547;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    8. 8.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1528;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
      Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
      Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1528;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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